Brain Sex? What is that? Some sort of cyber-intercourse?
No. ‘Brain sex’ is how many transgender activists explain how their condition came about. They specifically say that, ‘Transgender occurs when an individual of one sex has certain sex-related structures in the brain that are typical of the opposite sex.’
In other words, according to this notion, ‘brain sex’ is a physical condition and not a psychological one. Putting that more technically, what is being claimed is that what they call ‘transgender’ — not a scientific term — is caused by a form of intersexuality that is localised in the brain. This is ‘brain sex’. However, physical heteromorphism of this type should be observable. So is it?
Intersex — what is it?
To understand that you need to know a little bit more about what intersex is. In this, individuals of one chromosomal karotype –XX or XY — may be born with sex-related structures typical of the other. In a condition called Complete Androgen Insensitivity Syndrome, the individual, as birth, looks like a perfectly normal girl child.
She grows up to appear to be a typical, healthy woman. Then, when she is unable to get pregnant, testing is done and at this point it is discovered that she is actually XY — she has male-typical chromosomes. What has happened is that her body is insensitive to the masculinising effects of testosterone.
There are many intersex conditions, like Partial Androgen Insensitivity, for example. There’s Klinefelter’s Syndrome, where the individual has three sex chromosomes, XXY, ‘mosaic’ (XYXY), congenital adrenal hyperplasia (CAH) and a host of others.
While these intersex conditions are relatively rare, there are still a large number of people with them. They are found all over the world in all populations. In some cases, their genitalia differ greatly from the ‘normative’ and this led, in the past, to many unnecessary surgical interventions to ‘correct’ it. (Thankfully this is much less the case now, but if you have a child you think might be intersex, then please find out as much as you can before agreeing to surgeries.)
Most importantly, perhaps, we can directly observe the effects of these conditions, although in some, like CAIS, this might not be at all obvious till much later in life.
Trapped in the wrong body?
Transgender activists, through the brain sex hypothesis, are suggesting that something similar causes transsexualism, but the site of the heteromorphism is in the brain.
This has been linked to another idea popular with many transgender people, that they are ‘trapped in’ the wrong body. ‘Look,’ they say (if they are male-to-female) ‘I may have a man’s body but I have a woman’s brain.’
They are claiming that transsexualism is caused by a physical condition. Specifically, a brain-restricted form of intersex.
It’s not clear when exactly this claim was first made, but it was certainly current by the 1980s.
During that decade, a young scientist called Ray Blanchard was working at the Clarke Institute in Toronto, Canada. One of his roles was to provide letters of recommendation, for individuals seeking Genital Reconstruction Surgery (GRS) or a ‘sex change’.*
At that time, it had been broadly assumed that ‘True’ transsexuals were very like extremely feminine homosexual men. They were certainly physically attractive and very ‘passable’ as women. They tended to present while they were very young, often in their teens. But their most noticeable characteristic was a powerful sexual desire for men.
Blanchard had no difficulty with this group, but he soon realised he was seeing another group too. These were older, very masculine, didn’t look or act like women at all and — critically — were not primarily attracted to men.
However, they were in distress . So Blanchard began to develop an explanation that would allow him, ethically, to give them a letter of recommendation for GRS.
This difference had previously been noted by researchers and in most cases non-homosexual subjects were refused recommendation for GRS, because they were considered to be fetishistic transvestites.
Blanchard is a realist and he was not interested in the kind of pejorative thinking that would deny these people relief form their distress. So he carried our systematic statistical surveys over a period of years.
This allowed him to show that the non-homosexual subjects were actually exhibiting a condition he called ‘autogynephilia’ (AGP). This he described as ‘a man’s propensity to sexually aroused by the thought of himself as a woman’.
In accordance with this, Blanchard called the feminine, exclusively homosexual subjects ‘HomoSexual TransSexual (HSTS) and the masculine, non-homosexual ones AGP. The result was Blanchard’s Typology. Now, both types could legitimately be recommended for surgery, since both had a describable, albeit very different, condition that could be treated in this way.
Unfortunately, rather than being thankful for this intervention, the proponents of the ‘brain sex’ hypothesis were upset. They attacked Blanchard for calling HSTS ‘homosexual’. That was a ridiculous attack; they were males who were attracted to other males. However, they were not gay men, they were transsexuals. Hence, HSTS. (All the HSTS I have explained this to, have agreed that it is accurate; and in any case, this is science, not some touchy-feely Post-modernist woo. There is such a thing as objective reality and taxonomy matters.)
Misreading Blanchard, and misleading the world.
However, in a blatant misreading of Blanchard, they also attacked him
for saying that AGPs were just closet fetishists who put on women’s clothes to masturbate.
In fact, Blanchard defined three discrete orientations within AGP (bisexual, analloerotic or asexual, and gynephilic, attracted to women.) He also defined several different forms that AGP could take. So it’s a very broad description of an unusually complex condition and the only thing that holds it together is the core notion of being stimulated by the idea of being a woman, while also being attracted to women.
This cuts right across the ‘brain sex’ hypothesis, because this claims that inside their brains, these individuals are actually women.
Before we look at neurology, which is clearly the only science that might resolve this, we have to know a few things about the brain. It is the most adaptive organ in the body. Just thinking about something changes it. The brain makes new connections all the time, in response to new thoughts and things learned. It’s changing as we change.
For example, musicians have measurably different brains from non-musicians. But do their brains make them musicians or does being a musician change their brains?
Correlation is not causation.
What that means is that even if we were able to show that there were differences in brain morphology between transsexuals and other males, we could not just assume — as the ‘brain sex’ hypothesis does — that this makes them transsexual.
Establishing this would be next to impossible. Since changes in brain connections happen hand in hand with behavioural changes, we would have to test a random sample of children. We would have to note whether they had these, then observe them and see if they became transsexual, later. And all the while we would have to control for and exclude any influence that the experimental procedure itself might cause.
Good luck with designing that experiment and getting permission and funding to do it.
Brain sex in individuals.
Blanchard, aware of this, suggested that when it became possible to observe inside the brains of transsexuals, his HSTS type would be found to have brains more like women’s, whereas the AGPs would have men’s brains. Bear that in mind.
The ‘brain sex’ hypothesis got a major boost in 1996 when Zhou et al published results of autopsies on the brains of 6 MtF transsexuals. These were not controlled for HSTS/AGP. Zhou found heteromorphism in the BST corpus, which is a part of the amygdala, below the cerebrum.
‘Lo!’ claimed the ‘brain sex’ apologists, ‘We are vindicated! Transsexuals have women’s brains.’
They then argued that since the amygdala forms early in the embryo, this must be a precursor to transsexualism.
The problems were manifold. Firstly, just because an area of the brain forms early, does not mean it can’t change later. The BSTc is particularly subject to change under the stimulus of sex hormones. Six subjects is not enough to ‘prove’ anything; it’s an observation, that’s all. The notion of causation was moot and to be fair, Zhou never claimed that the BSTc anomaly ’caused ‘ transsexualism. Others did that, for political reasons.
Unfortunately, these obvious problems didn’t stop the ‘brain sex’ enthusiasts from seizing on Zhou and putting it centre-stage. They even got the legendary Bob Sapolsky, he of the huge beard, to go along with this.
However, as so often in science, it was to be overturned. In the first decade of the 21st century, MRI testing became cheap enough that it could be used for projects like this. In 2010 two teams set out to see if they could find out a bit more. Both these teams were experienced in using MRI testing in areas of sexuality, with proven track records.
One team, (Rametti et al) screened out AGPs by only testing exclusively homosexual subjects, and the other (Savic and Arver) screened out HSTS. So Rametti only scanned HSTS and Savic and Arver only scanned AGPs. These were large-scale studies with many controls were built in. They were conducted on individuals who had not yet commenced hormone treatment.
The results were compelling, as was repeated in Guillamon et al’s review paper, published in 2016.
Rametti found that HSTS have brains shifted toward the typical for women on ‘all tested parameters’. Savic and Arver found that AGP brains are no different from men’s.
This suggests two things.
As Guillamon put it, this, along with a welter of neurological evidence from other brains scans and autopsies, suggests two things. The first is that there is evidence for a localised form of brain intersexuality, but only in HSTS and not in AGPs. Secondly, Blanchard and, let us not forget, every serious researcher since Hirschfeld was right: there are two distinct types of Male to Feminine transsexuals — but only one of them has what might be called ‘brain sex’.
So where does that leave the ‘brain sex’ hypothesis? Well, in the first place, none of the testing, or Guillamon’s review, establishes causation. Brains are as likely to have been changed by behaviour as the other way around. As well as this, the principal advocates of the ‘brain sex’ hypothesis are identifiable as AGP. They have no such brain intersexuality, either as a result of their transsexualism or as a stimulus for it. They just have men’s brains.
So, maybe HSTS is caused by a form of brain intersexuality, or maybe being HSTS changes your brain; but if you’re non-homosexual, it doesn’t matter, because you have a standard man’s brain anyway.
The cause of non-homosexual transgender/transsexualism in males has nothing to do with ‘brain sex. It is caused by a paraphilia — and one that the subjects themselves have been nourishing, sometimes for decades, rewarding it by their own habits and making it stronger.
Oh what a surprise.
The principal arguments of AGPs, which they have ruthlessly pushed, consistently bullying and ‘no-platforming’ anyone who dared challenge them with science, have been shot to tatters.
There are indeed two types of MtF transsexual; and only one of them has a brain like a woman’s. That type is not the AGP. As far as they are concerned the ‘brain sex’ hypothesis — and they are the ones who have been pushing it — is dead in the water.
*The term ‘sex change’ is misleading. The surgery is purely cosmetic. The subject’s sex does not change in anyway. Strictly, the genitalia are reconstructed to look like those of a person of the opposite sex — sometimes very convincingly. Hence Genital Reconstruction Surgery or GRS.
Originally posted 2017-08-01 11:27:00.
Also published on Medium.